Sulodexide. Pharmacokinetics, pharmacodynamics, and mechanism of action

Sulodexide. Pharmacokinetics, pharmacodynamics, and mechanism of action

Authors

  • Luca Masotti Dirigente Medico Medicina Interna, Ospedale di Cecina, Livorno, Professore a Contratto, Università di Siena

DOI:

https://doi.org/10.7175/cmi.v4i4S.1088

Keywords:

Sulodexide, Pharmacokinetics, Pharmacodynamic, Mechanism of action

Abstract

Sulodexide is a highly purified preparation containing glycosaminoglycans composed from heparin-like and dermatan fractions. It is similar to unfractionated heparin, but it shows a prolonged half-life, a higher bioavability and a reduced effect on bleeding parameters. This article describes the mechanism of action of sulodexide and its pharmacokinetic and pharmacodynamic parameters, listing the most important pharmacologic studies published.

Downloads

Published

2015-10-13

Issue

Section

Case report
Loading...