Prescribing restrictions – a necessary strategy among some European countries to enhance future prescribing efficiency?

Authors

  • Brian Godman Department of Laboratory Medicine, Division of Clinical Pharmacology, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden
  • Rickard Malmström Department of Medicine, Clinical Pharmacology Unit, Karolinska Institutet, Karolinska University Hospital Solna, SE-17176, Stockholm Sweden
  • Marion Bennie Strathclyde Institute for Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, UK Information Services Division, NHS National Services Scotland, Edinburgh, UK
  • Solveig Sakshaug Department of Pharmacoepidemiology, Division of Epidemiology, Norwegian Institute of Public Health, Oslo, Norway
  • Thomas Burkhardt Hauptverband der Österreichischen Sozialversicherungsträger, Vienna, Austria
  • Stephen Campbell Primary Care Research Group, University of Manchester, UK
  • Kristina Garuoliene Faculty of Medicine (Department of Pathology, Forensic Medicine and Pharmacology), University of Vilnius, Vilnius, Lithuania Medicines Reimbursement Department, National Health Insurance Fund, Vilnius, Lithuania
  • Ulrich Schwabe University of Heidelberg, Institute of Pharmacology, Heidelberg, Germany
  • Luka Vončina Drugs and Medical Products, Croatian Institute for Health Insurance, Zagreb, Croatia
  • Lars L Gustafsson Department of Laboratory Medicine, Division of Clinical Pharmacology, Karolinska Institutet, Karolinska University Hospital Huddinge, SE 141 86, Stockholm, Sweden

DOI:

https://doi.org/10.7175/rhc.v3i1.55

Keywords:

Pharmaceuticals, Prescribing restrictions, Generics, Drug utilisation studies, Efficiency

Abstract

The unsustainable growth in pharmaceutical expenditure has resulted in multiple initiatives across Europe to lower prices of generics and enhance their utilisation. These include prescribing restrictions. However, there have been concerns with their impact on subsequent quality of care as well as their influence in reality. OBJECTIVES: (a) Review the influence of prescribing restrictions and whether there are any differences depending on their nature and drug classes; (b) Ascertain whether prescribing restrictions can be added to existing demand-side measures to further enhance prescribing efficiency; (c) Whether they compromise subsequent quality of care. RESULTS: Prescribing restrictions have a variable impact on subsequent utilisation of patented protected products versus generics in a class, with their influence depending on the nature and follow-up of the restrictions rather than the class of drug. This is seen among the proton pump inhibitors, statins, and renin-angiotensin drugs. Prescribing restrictions can be successfully added to existing measures to further enhance prescribing efficiency, and do not appear to compromise subsequent quality of care. CONCLUSIONS: Prescribing restrictions can be a successful strategy as countries strive to maintain the European ideals for healthcare. However, care is needed when planning these programmes: else health authorities could be disappointed with their outcome.

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Published

2011-11-14

Issue

Section

Narrative reviews