Systemic amyloidosis due to unknown multiple myeloma in small bowel pseudo-obstruction: case report

Systemic amyloidosis due to unknown multiple myeloma in small bowel pseudo-obstruction: case report

Authors

  • Giuseppe Caparrotti Division of Hematology, San Giuseppe Moscati Hospital, Aversa (CE), Italy
  • Diego Di Maria Division of Hematology, San Giuseppe Moscati Hospital, Aversa (CE), Italy
  • Elia Iovane Division of Hematology, San Giuseppe Moscati Hospital, Aversa (CE), Italy
  • Clemente Martone Division of Hematology, San Giuseppe Moscati Hospital, Aversa (CE), Italy
  • Francesco Graziani Division of Hematology, San Giuseppe Moscati Hospital, Aversa (CE), Italy
  • Giuseppina De Falco Division of Hematology, San Giuseppe Moscati Hospital, Aversa (CE), Italy
  • Daniela Esposito Division of Hematology, San Giuseppe Moscati Hospital, Aversa (CE), Italy
  • Claudio Marotta Division of Hematology, San Giuseppe Moscati Hospital, Aversa (CE), Italy
  • Giuseppina Papa Division of Hematology, San Giuseppe Moscati Hospital, Aversa (CE), Italy
  • Isidoro Orabona Division of Minimally Invasive Surgery and Endolaparoscopy, San Giuseppe Moscati Hospital, Aversa (CE), Italy
  • Davide Albino Rossetti Division of Minimally Invasive Surgery and Endolaparoscopy, San Giuseppe Moscati Hospital, Aversa (CE), Italy
  • Nicola Armiento Division of Minimally Invasive Surgery and Endolaparoscopy, San Giuseppe Moscati Hospital, Aversa (CE), Italy
  • Gennaro Ferrara Division of Minimally Invasive Surgery and Endolaparoscopy, San Giuseppe Moscati Hospital, Aversa (CE), Italy
  • Pasquale Pezzella Division of Minimally Invasive Surgery and Endolaparoscopy, San Giuseppe Moscati Hospital, Aversa (CE), Italy

DOI:

https://doi.org/10.7175/cmi.v10i1.1213

Keywords:

Myeloma, Amyloidosis, Pseudo-obstruction, Hypogammaglobulinemia, Congo red stain

Abstract

Amyloidosis is a pathologic diagnosis characterized by extracellular deposition of insoluble protein fibrils in various organs and tissues. There are two main forms of amyloidosis, primary amyloidosis, and secondary amyloidosis. Gastrointestinal involvement is common in both amyloidosis forms.

We describe the case of a 78-year-old woman taken to the operating room for small bowel obstruction, found to have pseudo-obstruction and enteritis. Exploratory laparotomy revealed gastric mass and histological examen showed extensive amyloid deposition consistent with amyloidosis. Hematological evaluation revealed unknown multiple myeloma. This case report and literature data suggest to perform a hematological examination in patients with amyloidosis diagnosis to exclude a multiple myeloma or other plasma cell disorders

References

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Published

2016-03-31

Issue

Vol. 10 No. 1 (2016)

Section

Case report

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