Myeloid Sarcoma Involving Kidneys: From Diagnosis to Treatment. Case Report and Literature Review

Myeloid Sarcoma Involving Kidneys: From Diagnosis to Treatment. Case Report and Literature Review

Authors

  • Francesca Guidotti Division of Hematology Department of Medicine, Valduce Hospital, Como, Italy https://orcid.org/0000-0002-9030-1557
  • Angelo Gardellini Division of Hematology Department of Medicine, Valduce Hospital, Como, Italy
  • Maddalena Feltri Department of Pathology, Valduce Hospital, Como, Italy
  • Michelle Zancanella Division of Hematology Department of Medicine, Valduce Hospital, Como, Italy
  • Vittoria Saccà Division of Hematology Department of Medicine, Valduce Hospital, Como, Italy
  • Luciana Ambrosiani Department of Pathology, Valduce Hospital, Como, Italy
  • Mauro Turrini Division of Hematology Department of Medicine, Valduce Hospital, Como, Italy

DOI:

https://doi.org/10.7175/cmi.v14i1.1460

Keywords:

Sarcoma, Acute Myeloid Leukemia, Kidney

Abstract

Myeloid sarcomas (MS) are rare extramedullary hematological tumors which generally occur during the natural course of acute myeloid leukemia or chronic myeloid leukemia. Rarely, their onset precedes peripheral blood and bone marrow manifestations of disease. Common sites of involvement are skin, bone, soft tissue, lymph nodes, reproductive or digestive organs, and central nervous system.

Herein, we report the case of a 72-year-old man affected by JAK2 V617F mutated myeloproliferative neoplasm who developed MS involving collecting system of both kidneys. MS and MS-related obstructive nephropathy were the first signs of the acute evolution of a known chronic hematological malignancy, preceding by some weeks the onset of leukocytosis.

 

References

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Published

2020-09-15

Issue

Vol. 14 No. 1 (2020)

Section

Case report

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