Risk factors for young ischemic stroke and the enigma of trombophilic polymorphisms: a case report

Risk factors for young ischemic stroke and the enigma of trombophilic polymorphisms: a case report

Authors

  • Linda Iurato UOC di Neurologia, Ospedale Sant’Ottone Frangipane, ASL Avellino, Ariano Irpino
  • Marialuisa Ventruto Laboratorio di Genetica Medica, Ospedale Moscati, Avellino
  • Maria Adalgisa Police Laboratorio di Genetica Medica, Ospedale Moscati, Avellino
  • Alessandro Morella Responsabile UOS Diagnostica Cardiologica, Ospedale Sant’Ottone Frangipane, ASL Avellino
  • Alfonso Fortunato Direttore Servizio di Emotrasfusione, Ospedale Sant’Ottone Frangipane, ASL Avellino, Ariano Irpino
  • Lanfranco Musto Direttore UOC Radiologia, Ospedale Criscuoli, ASL Avellino, Sant’Angelo dei Lombardi
  • Patrizia Fiori UOC di Neurologia, Ospedale Sant’Ottone Frangipane, ASL Avellino, Ariano Irpino
  • Mario Nicola Vittorio Ferrante Direttore Distretto Sanitario di Mirabella, ASL Avellino, Mirabella Eclano
  • Antonio Monaco Direttore UOC di Neurologia, ASL Avellino, Ariano Irpino

DOI:

https://doi.org/10.7175/cmi.v5i4.497

Keywords:

Young stroke, Thrombophilia, Ischemic risk factors

Abstract

We report the case of a 48-year-old female patient with stroke family history that was admitted in our ward with suspected ischemic stroke diagnosis. The diagnostic process is described in detail, paying attention in particular to anamnestic data and to genetic polymorphisms related to higher risk for inherited thrombophilia. At the end, the diagnosis indicates red infarct in a migraine patient with cerebrovascular and cardiovascular risk factors of undetermined aetiology according to TOAST criteria. Some of the known thrombophilic polymorphisms were found in the patient: however not all the mentioned thrombophilic markers are universally recognized as predisposing factors for arterial ischemic stroke.

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Published

2011-12-15

Issue

Vol. 5 No. 4 (2011)

Section

Case report

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