A severe infective endocarditis successfully treated with linezolid

A severe infective endocarditis successfully treated with linezolid

Authors

  • Graziano Antonio Minafra S.C. Medicina Interna - Ospedale “G. Tatarella” – Cerignola - ASL FG (direttore Dott. Francesco Ventrella)
  • Donatella Concetta Cibelli S.C. Medicina Interna - Ospedale “G. Tatarella” – Cerignola - ASL FG (direttore Dott. Francesco Ventrella)
  • Maria Pipino S.C. Medicina Interna - Ospedale “G. Tatarella” – Cerignola - ASL FG (direttore Dott. Francesco Ventrella)
  • Vincenzo Dargenio S.C. Medicina Interna - Ospedale “G. Tatarella” – Cerignola - ASL FG (direttore Dott. Francesco Ventrella)
  • Francesco Ventrella S.C. Medicina Interna - Ospedale “G. Tatarella” – Cerignola - ASL FG (direttore Dott. Francesco Ventrella)

DOI:

https://doi.org/10.7175/cmi.v4i1.538

Keywords:

Streptococcus bovis, Prosthetic valve endocarditis, Infective endocarditis, Linezolid

Abstract

Despite significant improvements in surgical and medical therapy, prosthetic valve endocarditis (PVE) is a diagnostic and therapeutic challenge and is often associated with a severe prognosis. We report a case of a 59-year-old woman, with  PVE and bacterial endocarditis (Streptococcus bovis) successfully treated with linezolid. Linezolid is a bacteriostatic oxazolidinone antibiotic that has been proven to be effective for the treatment of patients with pneumonia, skin and soft tissue infections, and infections due to Gram-positive cocci. Linezolid is not yet recognised as a standard therapy for infective endocarditis, but its use becomes a necessity when infection is due to multidrug-resistant microorganisms.

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Published

2010-03-15

Issue

Vol. 4 No. 1 (2010)

Section

Case report

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