Severe invasive methicillin-resistant S. aureus (USA300 clone) infection in an Italian adolescent

Severe invasive methicillin-resistant S. aureus (USA300 clone) infection in an Italian adolescent

Authors

  • Piero Valentini Istituto di Clinica Pediatrica, Università Cattolica del Sacro Cuore
  • Donatella Angelone Istituto di Clinica Pediatrica, Università Cattolica del Sacro Cuore
  • Francesca Crea Divisione di Endocrinologia, Ospedale Pediatrico “Bambino Gesù”
  • Annalisa Pantosti Dipartimento di Malattie Infettive, Parassitarie e Immunomediate, Istituto Superiore di Sanità, Roma

DOI:

https://doi.org/10.7175/cmi.v3i4.540

Keywords:

MRSA, Sepsis, Meningitis, Necrotizing pneumonia, Antibiotic resistance

Abstract

This report describes an uncommon presentation of invasive community-acquired methicillin-resistant S. aureus (CA-MRSA) infection in an immunocompetent adolescent without any other risk factor, characterized by septicaemia, meningitis, necrotising pneumonia and deep venous thrombosis (DVT). Successful treatment was performed with linezolid, rifampicin and low-molecular-weight heparin (LMWH). MRSA molecular typing revealed the presence of Panton-Valentine leukocidin (PVL) gene, and a genetic background identical to USA300 clone, an emerging aggressive CA-MRSA strain in USA and Europe.

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Published

2009-12-15

Issue

Vol. 3 No. 4 (2009)

Section

Case report

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